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| Vendor: | PTCB |
|---|---|
| Exam Code: | PTCE |
| Exam Name: | Pharmacy Technician Certification (CPhT) Exam |
| Exam Questions: | 223 |
| Last Updated: | February 27, 2026 |
| Related Certifications: | Pharmacy Technician Certification |
| Exam Tags: | PTCB Pharmacology Professional Level Pharmacy TechniciansPharmacy Managers |
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A pharmacy technician should notify a pharmacist when a refill of sertraline is requested if the patient:
Sertraline (Zoloft)is anSSRI antidepressantused formajor depressive disorder (MDD), anxiety, and other mood disorders.Suicidal ideation(thoughts of self-harm) is aserious and potentially life-threatening side effect, especially inyoung adults. A pharmacy technicianmust notify the pharmacist immediatelyif a patient reportssuicidal thoughts, as this may require immediate medical intervention.
A . Presents new insurance coverage Incorrect; this is an administrative issue, not a clinical concern.
B . Requests the refill two days early Incorrect; a slight early refill request does not indicate a safety concern.
D . Reports improved interest and motivation Incorrect; this is apositive treatment response, not an urgent issue.
Other Answer Choices Explained:Reference:
FDA Black Box Warning for SSRIs -- Suicide Risk in Young Adults
PTCB PTCE Exam Content Outline (Medication Safety & Patient Communication)
Lexicomp Drug Monograph for Sertraline (Zoloft)
Which of the following medications is aproton pump inhibitor (PPI)?
Prilosec (omeprazole) is a PPIused to reduce stomach acid forGERD and ulcers.
Reference:FDA PPI Drug Classification Guide.
According to the FDA, a Medication Guide must be given to the patient when dispensing:
TheU.S. Food and Drug Administration (FDA)requires aMedication Guide (MedGuide)to be provided when dispensing certain medications that have significant safety concerns.Zyprexa (Olanzapine), anatypical antipsychotic, requires aMedication Guidedue to serious risks such as:
Increased mortality in elderly patients with dementia-related psychosis
Metabolic side effects(e.g., weight gain, hyperglycemia, and dyslipidemia)
Neuroleptic malignant syndrome (NMS)
A . Zafirlukast Incorrect; while used forasthma(leukotriene receptor antagonist), it doesnot require a Medication Guide.
B . Zestril (Lisinopril) Incorrect; anACE inhibitorfor hypertension, it doesnot require a Medication Guide.
C . Zinc Incorrect; adietary supplementthat does not require a Medication Guide.
Other Answer Choices Explained:Reference:
FDA Medication Guide Requirements for Olanzapine (Zyprexa)
PTCB PTCE Exam Content Outline (Medication Safety & Patient Counseling)
Handling hazardous substances should be done:
Comprehensive and Detailed Step-by-Step Explanation:
Hazardous drugs (HDs)must be handled withpersonal protective equipment (PPE), including:
Gloves (chemotherapy-rated)
Gown (disposable, impermeable material)
Eye protection (if splashing risk exists)
Respirator (if airborne exposure is possible)
Explanation of Answer Choices:B. Wearing personal protective equipmentCorrect.USP <800> mandatesPPEfor handling hazardous drugs.A. In a chemical safety cabinet Incorrect.Only sterile hazardous drugs require a biological safety cabinet.C. Using disposable gloves washed between each use Incorrect.Disposable gloves should be discarded, not washed.D. In a positive-pressure clean room Incorrect.Hazardous drugs require negative pressure rooms, not positive pressure.
Reference:
USP <800>: Hazardous Drug Handling
NIOSH Guidelines on PPE for Hazardous Drugs
According to the Centers for Disease Control and Prevention (CDC), use of an alcohol-based hand sanitizer is indicated for healthcare personnel who:
According to theCDC Hand Hygiene Guidelines,alcohol-based hand sanitizershould be used:
Before and after direct patient contact(if hands are not visibly dirty).
Before and after wearing gloves(if no contamination is visible).
Before handling medication or sterile supplies.
A . Are about to touch a contaminated surfaceIncorrect
Hand sanitizer should not be used before touching a contaminated surface.Instead, gloves should be worn, and hand hygiene should be performedaftertouching a contaminated surface.
B . Have just performed an aseptic taskIncorrect
Before aseptic tasks (e.g., preparing IV medications), soap and water or hand sanitizer is used.Afterward, contamination risk determines if sanitization is needed.
C . Are about to remove their glovesIncorrect
Gloves do not completely prevent contamination; hand hygiene should be performedafterremoving gloves, not before.
CDC Guidelines for Hand Hygiene in Healthcare Settings-- Recommends hand sanitizer use after patient contact.
USP <797> Sterile Compounding Guidelines-- Reinforces aseptic hand hygiene practices.
PTCB PTCE Exam Content Outline-- Covers infection control and proper use of hand hygiene techniques.
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